{ "_id": "6a229a1ccd65a98ecbd574eb", "Package": "PLIS", "Type": "Package", "Title": "Multiplicity Control using Pooled LIS Statistic", "Version": "1.2", "Date": "2022-10-01", "Author": "Zhi Wei & Wenguang Sun", "Maintainer": "Zhi Wei ", "Description": "A multiple testing procedure for testing several groups of\nhypotheses is implemented. Linear dependency among the\nhypotheses within the same group is modeled by using hidden\nMarkov Models. It is noted that a smaller p value does not\nnecessarily imply more significance due to the dependency. A\ntypical application is to analyze genome wide association\nstudies datasets, where SNPs from the same chromosome are\ntreated as a group and exhibit strong linear genomic\ndependency. 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